Biocatalysis for the Pharmaceutical Industry (eBook)

Biocatalysis is rapidly evolving into a key technology for the
discovery and production of chemicals, especially in the
pharmaceutical industry, where high yielding chemo-, regio-, and
enantioselective reactions are critical. Taking the latest
breakthroughs in genomics and proteomics into consideration,
Biocatalysis for the Pharmaceutical Industry concisely yet
comprehensively discusses the modern application of biocatalysis to
drug discovery, development, and manufacturing. Written by a team
of leading experts, the book offers deep insight into this cutting
edge field.

* Covers a wide range of topics in a systematic manner with an
emphasis on industrial applications

* Provides a thorough introduction to the latest biocatalysts,
modern expression hosts, state-of-the-art directed evolution, high
throughput screening, and bioprocess engineering

* Addresses frontier subjects such as emerging enzymes,
metabolite profiling, combinatorial biosynthesis, metabolic
engineering, and autonomous enzymes for the synthesis and
development of chiral molecules, drug metabolites, and
semi-synthetic medicinal compounds and natural product analogs

* Highlights the impact of biocatalysis on green chemistry

* Contains numerous graphics to illustrate concepts and
techniques

Biocatalysis for the Pharmaceutical Industry is an
essential resource for scientists, engineers, and R&D policy
makers in the fine chemical, pharmaceutical, and biotech
industries. It is also an invaluable tool for academic researchers
and advanced students of organic and materials synthesis, chemical
biology, and medicinal chemistry.